Spline cast

Spline doctors released their first podcast about to spline or not to spline.
I learned animation from them so that I know what they said in the podcast. However, I think there is no right or wrong way to animate. Personally I don't use liner knots except pupils. I even use spline for pupils sometimes. I used stepped or constant mode and spline depending on the type of a shot I have. If you've already listened to their podcast, I like spline becase it gives me closer idea and look to the final animation because the final animation is spline like Dr. Angus said in the podcast. However, I've tried some different ways of animating and made a bunch of crappy animation and then found the way of animating that I like.
I would say, try different ways, like stepped, spline or liner, you'll see what works better or best for ya.